Recently widowed Doctor Michael Hfuhruhurr, the world's greatest neurosurgeon, injures Dolores Benedict in a car accident. He operates on her and saves her life using a technique of his own invention: cranial screw-top brain entry. As Benedict recovers, Hfuhruhurr falls in love with her and they are soon married. However, Benedict is only interested in Hfuhruhurr's money and Hfuhruhurr still yearns for his previous wife. They travel to Vienna to attend a medical conference where Hfuhruhurr finally divorces Dolores, meets a mysterious Doctor Alfred Necessiter and becomes entangled in a series of murders committed by The Elevator Killer.

Wes Block is a detective who's put on the case of a serial killer. His victims are young and pretty women, which he rapes and murders. The murders are getting personal when the killer chooses victims who are acquaintances of Block. Even his daughters are threatened.